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Bench2Bio

Selected work

What investors would test, and what we built.

Each case is described by stage, modality and practice. Client names are withheld by default; references are available after an NDA.

Putting the strongest evidence first

Stage
Seed
Modality
Women's health therapeutic
Practice
Fundraising strategy and materials
Timeline
3 to 5 days

The challenge

A well-protected asset with published preclinical data, a recognized clinical lead and written interest from a pharma company. The deck opened with regulatory detail, and the strongest credibility points arrived near the end.

What investors would test

  • Is the regulatory pathway a real shortcut, or a risk?
  • Who would partner on this, and why now?
  • Can a generalist investor follow the clinical data?

What we built

A reordered narrative that leads with the problem and the evidence, condensed clinical slides for a mixed audience, slide-by-slide rewrites and a tiered investor shortlist.

What changed

The team went into a pitch competition the following week leading with the problem, the data and the partner interest, instead of the regulatory background.

Platform or lead program?

Stage
Series A
Modality
Platform therapeutics
Practice
Fundraising strategy and materials
Timeline
3 to 5 days

The challenge

A strong preclinical package, including head-to-head results against standard of care, and well-known early investors. The deck had no ask, no competitive landscape and no exit path, and moved between a broad platform and a single lead indication.

What investors would test

  • Is this a platform or a product, and what does the Series A buy?
  • Why did earlier approaches to this biology fall short?
  • Who acquires or partners at the next inflection?

What we built

A new deck architecture that leads with the lead indication and frames the platform as upside, a competitive landscape against first-generation approaches, an ask tied to milestones, and a list of specialist funds.

What changed

One coherent story: a lead program investors can underwrite, and a platform that explains why they should stay for the next round.

Projections investors can believe

Stage
Seed
Modality
Medical device
Practice
Financial models and valuation
Timeline
3 to 5 days

The challenge

Granted patents and real policy traction, but two different raise amounts in the same deck, and revenue projections that ran ahead of the clinical and regulatory evidence.

What investors would test

  • How big is the first market, really?
  • What exactly does this round prove?
  • Which claims survive diligence?

What we built

A reconciled ask, projections rebuilt on defensible assumptions, a tighter bottom-up market size, and a list of claims to substantiate or remove.

What changed

A deck and a set of numbers that tell the same story, ready for medtech seed investors and hospital system venture arms.

One source of truth

Stage
Pre-seed
Modality
AI software for biopharma
Practice
Commercial strategy
Timeline
3 to 5 days

The challenge

Strong founder-market fit and two signed pilots, but the deck, one-pager and outreach note used different numbers, and the round needed a check against the stage.

What investors would test

  • Is the traction real, and will pilots convert?
  • How does this win against a well-funded adjacent player?
  • Is the round sized and priced for the stage?

What we built

One set of figures across every document, traction reframed around the pilots, sharper positioning against the adjacent player, and a pressure test of round size and valuation.

What changed

Materials ready for vertical AI, techbio and enterprise software investors who understand regulated buyers.

What founders say

“He is very thorough and it is demonstrated in the work output. Our deck was a compromise: great content, less than great format. He recognized it, understood why I made those decisions, but explained that we need to be firing on all cylinders. It changed my perspective.”

Gary Kellstrom, Jr.

CEO and Founder

01 / 03

Show the work

What the deliverables look like.

Illustrative exhibits. Clients keep every file, model and draft.

Exhibit A · Models and valuation

From headline value to risk-adjusted value

Illustrative only. Phase transition rates are rounded industry averages (BIO, 2011 to 2020); real models use asset-specific inputs and costs.

Exhibit B · Fundraising materials

Slide titles that carry the argument

Market Opportunity: $42B TAM

18,000 US patients a year fail first-line therapy. We start there.

Our Platform

One assay, three readouts: a two-week workflow becomes a two-hour test.

Illustrative only. An investor should understand the deck from its titles alone.

Exhibit C · Investor targeting

A tiered list, not a long list

TierInvestorCheckWarm path
1Specialist seed fund, can lead$1M to $3MBoard advisor
1Corporate venture arm$1M to $5MMentor
2Angel group syndicate$250K to $1MDirect
3Family office$250K to $2MCo-investor
Illustrative structure. Real lists are matched on stage, thesis, check size and recent activity.

Selected companies we have worked with

  • Altin Biosciences
  • Deciduous Therapeutics
  • KickIN Bio
  • BioGuard UVC
  • Node Biosciences
  • TippingPoint Biosciences
  • Receptor.AI
  • Gero
  • Sayenza Bio
  • ARC Medical
  • Artenga
  • Pharma Acuity
  • The Clinical Trials Network
  • Inovalon
  • PartsSource

Book a 20-minute call

Let's talk about what you're building.

Vadim Shepel

You'll speak with Vadim Shepel

Founder and Principal, Bench2Bio

  1. 01

    Where you are

    Your stage, your science and what is coming next: a raise, a partner conversation or a decision.

  2. 02

    What investors or partners will test

    An honest read on the gaps that will matter most, even if we never work together.

  3. 03

    Whether and how we can help

    A recommended starting point, or a referral if someone else is a better fit.

Prefer email? vadim@bench2bio.com

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